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Biotransformation Chemist Internship

Company: Hypha Discovery Limited

Placement title: Chemist - Biocatalysis - Royal Society of Chemistry internship
Length of placement: 3 months, full time
Location: Milton Science Park, Abingdon, OX14 4SD
Working hours: 08:30-17:00 Monday-Friday
Start date: September 2020 (there is some flexibility in the start date)
Salary and holiday allowance: £16,000 pro rata (£4,000 for the 3-month internship)

In this lab-based role, the intern will spend time on a research project to further exemplify the use of Hypha’s new enzyme reagents to synthesise conjugated drug metabolites. The intern will gain experience in biocatalysis together with analytical chemistry and purification techniques, and the use of a range of chromatography equipment. This internship is funded by the Royal Society of Chemistry Internship Grant Scheme.

Job description and duties

  • Identify and source suitable and cost-effective substrate compounds for exemplification
  • Conduct enzyme reactions with substrates using recombinant glucuronidating and glycosylating enzymes created in house by Hypha’ molecular biology and biochemistry team
  • Extract reactions and analyse for products of interest by UPLC-MS
  • Optimise and scale-up reactions to purify and confirm the identity of the products
  • Record and present the findings of these studies at internal meetings
  • Adhere to company Health and Safety policies and lab procedures. 

    Full training will be provided in standard operating procedures, lab safety and executing and analysing experiments.

    For more information and how to apply please refer to the additional information provided in the attachment.


No agencies please.


Contact details

Julia Shanu-Wilson

Email - julia.shanuwilson@hyphadiscovery.co.uk

Phone - 07909 873543

To apply for this vacancy please get in touch with the recruiter using the details shown above.

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Submission Terms and Conditions

Terms and conditions for submitting a vacancy onto Milton Park’s website: www.miltonpark.co.uk

  • This job vacancy must be based only on Milton Park
  • The company must be a Milton Park occupier
  • This job vacancy will remain live for 3 months or until further notice from yourself
  • This upload will be reviewed by the Marketing Manager for MEPC before it is set live, once it is set live you will receive a confirmation email
  • Please endeavour to contact the Marketing Manager to ensure the vacancy is removed once the position has been filled